Coleman Lindsley Lab
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The Hematologic Malignancies Data Repository (HMDR)

Integration of highly curated clinicopathologic data and next-generation sequencing data is a central challenge in translational research. We developed the Hematologic Malignancies Data Repository (HMDR) as a way to enhance the scope and uniformity of clinical data and promote research in hematologic malignancies at DFCI. 
  • Systematic abstraction of high-quality clinical and genetic data: we defined a set of core clinical and genetic data elements for all patients, augmented by additional high value data elements for specific diseases.
  • Enable access to integrated, de-identified data: to facilitate hypothesis generation, study design, and feasibility assessment, these curated data are made available to investigators through cBio@DFCI in collaboration with the Knowledge Systems Group.
  • Facilitate access to data and promote conduct of research: we function as a research support team through establishment of a step-by-step data request pipeline that guides users through cohort generation, governance, IRB application, and data delivery. ​

For more information about HMDR, click here.
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©2019 Lindsley Lab at Dana-Farber Cancer Institute
  • HOME
  • PEOPLE
  • RESEARCH
    • Stem Cell Transplantation
    • Bone Marrow Failure and MDS/AML Predisposition
    • Pathways of leukomogenesis
    • Hematologic Malignancies Data Repository
  • PUBLICATIONS
  • CONTACT
  • JOIN THE LAB
  • FUNDING SUPPORT
  • LAB PORTAL